Ancaster, ON – On the most basic level, the difference between monoclonal vs polyclonal antibodies is that monoclonals come from a single cell lineage whereas polyclonals are secreted by different B cell lineages. Researchers from Affinity Biologicals Inc. manufacture both types of antibodies, but prefer polyclonals in biological research studies for a number of different reasons.

Due to the fact that polyclonal antibodies come from different cells, they contain multiple recognition sites on an antigen and the apparent affinity and avidity of antigen-antibody interactions is very high. In addition, polyclonal antibodies are also far more cost-effective than monoclonal antibodies and do not require sophisticated equipment or expertise.

Despite the superior advantages that polyclonals offer, both antibodies have their own distinct set of advantages. For example, monoclonal antibodies are ideal for identifying single proteins and can target varied kinds of cancer.

Affinity Biologicals Inc. has several antibody based ELISA kits that are used in the quantification of factor VII, factor VIII, factor IX, and  factor XI antigen levels. To learn more about the differences between monoclonal vs. polyclonal antibodies and their applications visit Affinity Biological Inc.’s website at

About Affinity Biologicals Inc.

Affinity Biologicals is a renowned name associated with the medical research and diagnostics industry since 1987. The company has manufactured over 250 reagents used internationally in the research and diagnostics of hemostasis and thrombosis to date. The product range of Affinity Biologicals include coagulation antibodies, deficient plasmas, antibody sets of ELISA, control plasmas, custom plasmas, and factor inhibitor plasmas.

Contact Details

Affinity Biologicals Inc.


1395 Sandhill Drive, Ancaster, ON, Canada L9G 4V5.




(905) 304-9896


(905) 304-9897

Toll Free: 1-800-903-6020