What Is the Difference between Polyclonal vs Monoclonal Antibodies?

If you are currently looking for a secondary antibody to help in your research, you may be wondering of the difference between polyclonal vs monoclonal While both polyclonal and monoclonal antibodies are extracted from the immune system of various animals, polyclonals use larger mammals, whereas monoclonals use smaller creatures.

While both antibodies have their own distinct set of benefits and disadvantages, for the most part, research facilities choose to use polyclonals for the following advantages. Unlike monoclonal antibodies polyclonals:

  • – Are more cost-effective
  • – Are easier to produce
  • – Do not require complex production procedures
  • – Do not require sophisticated material/expertise to use

Monoclonals, on the other hand, offer what polyclonals cannot by offering researchers the ability to identify single proteins and different types of cancer. In addition, monoclonal antibodies are also more likely to show unanticipated cross reactions with unrelated antigens and produce large amounts of identical antibodies.

To find out more about which secondary antibody is ideal for your specific research applications, visit the Affinity Biologicals Inc. website today at https://affinitybiologicals.com/. Remember that it is important not to use any of Affinity Biologicals Inc.’s products for diagnostic purposes, only research purposes.